Article
Cementum-forming cells are phenotypically distinct from bone-forming cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Jan 2000
Grzesik W J, Cheng H, Oh J S, Kuznetsov S A, Mankani M H, Uzawa K, Robey P G, Yamauchi M
Abstract excerpt
Normal human cementum-derived cells (HCDCs), expanded in vitro, formed mineralized matrix when attached to a ceramic carrier and transplanted subcutaneously into immunodeficient mice. The mineralized matrix elaborated by transplanted HCDC exhibited several features identical to cementum in situ and was significantly different from bone deposited by similarly transplanted human bone marrow stromal cells (BMSCs)....
Topics
- Adolescent
- Bicuspid
- Bone Marrow Cells
- Cells, Cultured
- Child
- Dental Cementum
- Humans
- Immunohistochemistry
- Phenotype
