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Article

A chronic hypercoagulable state in patients with beta-thalassaemia major is already present in childhood.

British journal of haematology - 1 Dec 1999

Eldor A, Durst R, Hy-Am E, Goldfarb A, Gillis S, Rachmilewitz E A, Abramov A, MacLouf J, Godefray Y C, De Raucourt E, Guillin M C

Abstract excerpt

A higher than normal incidence of thromboembolic events has been observed in adult patients with beta-thalassaemia major (TM) and certain haemostatic anomalies found in these patients suggest the existence of a chronic hypercoagulable state. Thalassaemic red blood cells (RBC) were demonstrated to facilitate thrombin formation due to altered asymmetry of the membrane phospholipids with enhanced exposure of...

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PMID: 10606878
DOI: 10.1046/j.1365-2141.1999.01758.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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