Article
Growth retardation in Turner syndrome: aneuploidy, rather than specific gene loss, may explain growth failure.
The Journal of clinical endocrinology and metabolism - 1 Dec 1999
Haverkamp F, Wölfle J, Zerres K, Butenandt O, Amendt P, Hauffa B P, Weimann E, Bettendorf M, Keller E, Mühlenberg R, Partsch C J, Sippell W G, Hoppe C
Abstract excerpt
The etiology of short stature (SST) in Turner syndrome (TS) is still a subject of speculation. A variety of hypotheses have been put forward, from SST as a result of increased intrauterine tissue pressure after fetal lymphedema to haploinsufficiency of a specific growth gene(s). These hypotheses have various statistical-auxological implications on the growth distribution in TS. Empirical research has provided no...
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