Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Severe intra-uterine growth retardation in a patient with maternal uniparental disomy 22 and a 22-trisomic placenta.

Prenatal diagnosis - 1 Nov 1999

Balmer D, Baumer A, Röthlisberger B, Schinzel A

Abstract excerpt

We report on a maternal uniparental disomy of chromosome 22 in a patient with severe intra-uterine growth retardation. Karyotyping of a placental tissue revealed non-mosaic trisomy 22, whereas lymphocyte chromosomes from the newborn were normal 46,XY. Microsatellite analysis using DNA extracted from white blood cells showed maternal uniparental heterodisomy for chromosome 22. Thus, the conceptus started as...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Disorders
Share to Chromosomes, Human, Pair 22

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Fetal Growth Retardation

Share to Lymphocytes

Share to Mosaicism

Share to Mothers

Share to Placenta

Share to Trisomy

Source

Identifiers

PMID: 10589061
DOI: 10.1002/(sici)1097-0223(199911)19:11<1061::aid-pd687>3.0.co;2-q

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Severe intra-uterine growth retardation in a patient with maternal uniparental disomy 22 and a 22-trisomic placenta.PMID 10589061Read ↗

A second case of intrauterine growth retardation and primary hypospadias associated with a trisomy 22 placenta but with biparental inheritance of chromosome 22 in the fetus.Semantic proximity Read ↗

MATERNAL UNIPARENTAL DISOMY OF CHROMOSOME 2 AND CONFINED PLACENTAL MOSAICISM FOR TRISOMY 2 IN A FETUS WITH INTRAUTERINE GROWTH RESTRICTION, HYPOSPADIAS, AND OLIGOHYDRAMNIOSSemantic proximity Read ↗

Maternal uniparental disomy for chromosome 22 in a child with generalized mosaicism for trisomy 22.Semantic proximity Read ↗

MATERNAL UNIPARENTAL DISOMY FOR CHROMOSOME 2 IN ASSOCIATION WITH CONFINED PLACENTAL MOSAICISM FOR TRISOMY 2 AND SEVERE INTRAUTERINE GROWTH RETARDATIONSemantic proximity Read ↗

Clinical and molecular studies in full trisomy 22: further delineation of the phenotype and review of the literature.Semantic proximity Read ↗

Maternal uniparental disomy 22 has no impact on the phenotype.Semantic proximity Read ↗

Maternal uniparental heterodisomy for chromosome 2: detection through ‘atypical’ maternal AFP/hCG levels, with an update on a previous caseSemantic proximity Read ↗

Prenatal diagnosis of low-level mosaicism for trisomy 21 by amniocentesis in a pregnancy associated with maternal uniparental disomy of chromosome 21 in the fetus and a favorable outcomeSemantic proximity Read ↗

Prenatal diagnosis of maternal uniparental disomy 21 in association with low-level mosaic trisomy 21 at amniocentesis in a pregnancy associated with intrauterine growth restriction and a favorable outcomeSemantic proximity Read ↗

[Prenatal diagnosis and genetic counseling in 19 cases with 22q11.2 microduplications].Semantic proximity Read ↗

Severe intrauterine growth restriction and trisomy 15 confined placental mosaicism: a case report and review of literatureSemantic proximity Read ↗

Prenatal diagnosis of 24 cases of microduplication 22q11.2: an investigation of phenotype-genotype correlationsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.