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Article

Evidence for autoregulation of cystathionine gamma-synthase mRNA stability in Arabidopsis.

Science (New York, N.Y.) - 12 Nov 1999

Chiba Y, Ishikawa M, Kijima F, Tyson R H, Kim J, Yamamoto A, Nambara E, Leustek T, Wallsgrove R M, Naito S

Abstract excerpt

Control of messenger RNA (mRNA) stability serves as an important mechanism for regulating gene expression. Analysis of Arabidopsis mutants that overaccumulate soluble methionine (Met) revealed that the gene for cystathionine gamma-synthase (CGS), the key enzyme in Met biosynthesis, is regulated a...

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Identifiers

PMID: 10558994
DOI: 10.1126/science.286.5443.1371

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-10558994-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

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Evidence for autoregulation of cystathionine gamma-synthase mRNA stability in Arabidopsis.PMID 10558994Read ↗

Identification of a short highly conserved amino acid sequence as the functional region required for posttranscriptional autoregulation of the cystathionine gamma-synthase gene in Arabidopsis.Semantic proximity Read ↗

Mechanisms to account for maintenance of the soluble methionine pool in transgenic Arabidopsis plants expressing antisense cystathionine gamma-synthase cDNA.Semantic proximity Read ↗

Constitutive overexpression of cystathionine gamma-synthase in Arabidopsis leads to accumulation of soluble methionine and S-methylmethionine.Semantic proximity Read ↗

A halt in poly(A) shortening during S-adenosyl-L-methionine-induced translation arrest in CGS1 mRNA of Arabidopsis thaliana.Semantic proximity Read ↗

Functional characterization of a methionine gamma-lyase in Arabidopsis and its implication in an alternative to the reverse trans-sulfuration pathway.Semantic proximity Read ↗

The N-terminal region of Arabidopsis cystathionine gamma-synthase plays an important regulatory role in methionine metabolism.Semantic proximity Read ↗

Differential response of methionine metabolism in two grain legumes, soybean and azuki bean, expressing a mutated form of Arabidopsis cystathionine γ-synthase.Semantic proximity Read ↗

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A single-nucleotide mutation in a gene encoding S-adenosylmethionine synthetase is associated with methionine over-accumulation phenotype in Arabidopsis thaliana.Semantic proximity Read ↗

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Analysis of the sulfur-regulated control of the cystathionine γ-lyase gene of Neurospora crassa.Semantic proximity Read ↗

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