Article
Differentiation of<i>Coxiella burnetii</i>isolates by sequence determination and PCR-restriction fragment length polymorphism analysis of isocitrate dehydrogenase gene
1 Nov 1999
Abstract excerpt
The isocitrate dehydrogenase (icd) gene of Coxiella burnetii was cloned and sequenced to differentiate between isolates with various geographic origins and phenotypic properties. Based on the gene sequences all 19 isolates studied could be divided into three groups. Group 1 contained isolates originating from acute cases of Q fever, ticks and cows. Groups 2 and 3 included isolates from chronic Q fever patients...
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