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Article

Temporal and spatial analysis of Sin Nombre virus quasispecies in naturally infected rodents.

Journal of virology - 1 Nov 1999

Feuer R, Boone J D, Netski D, Morzunov S P, St Jeor S C

Abstract excerpt

Sin Nombre virus (SNV) is thought to establish a persistent infection in its natural reservoir, the deer mouse (Peromyscus maniculatus), despite a strong host immune response. SNV-specific neutralizing antibodies were routinely detected in deer mice which maintained virus RNA in the blood and lungs. To determine whether viral diversity played a role in SNV persistence and immune escape in deer mice, we measured...

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Identifiers

PMID: 10516063
DOI: 10.1128/JVI.73.11.9544-9554.1999
PMCID: PMC112989

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