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Increased nuchal translucency in trisomy 13 fetuses at 10-14 weeks of gestation

17 Sept 1999

Abstract excerpt

In a multicenter screening study for trisomy 21 involving ultrasonographic measurement of fetal nuchal translucency thickness (NT) at 10-14 weeks of gestation, 100,311 singleton pregnancies with a live fetus were examined. There were 46 cases of trisomy 13, and in 33 (72%) of these, the NT was above the 95th centile. The estimated risk for trisomy 21, based on maternal age-related risk for this chromosomal...

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Identifiers

PMID: 10482866
DOI: 10.1002/(sici)1096-8628(19990917)86:3<205::aid-ajmg2>3.0.co;2-n

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