Article
Adult-type metachromatic leukodystrophy with a compound heterozygote mutation showing character change and dementia.
Psychiatry and clinical neurosciences - 1 Jun 1999
Fukutani Y, Noriki Y, Sasaki K, Isaki K, Kuriyama M, Kurosawa K, Ida H
Abstract excerpt
A 26-year-old Japanese woman slowly developed a change of character such as hypospontaneity and blunted affect, followed by obvious mental deterioration. She was diagnosed as having a disorganized type of schizophrenia at the first examination. Brain magnetic resonance imaging demonstrated diffuse high intensity in the cerebral white matter, particularly in the frontal lobes. The single photon emission computed...
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