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Article

Characterisation of a recent virulent transmissible gastroenteritis virus from Britain with a deleted ORF 3a.

Archives of virology - 1 Jan 1999

McGoldrick A, Lowings J P, Paton D J

Abstract excerpt

Analyses of transmissible gastroenteritis virus (TGEV) and porcine respiratory coronavirus (PRCV) isolates have suggested that tropism and pathogenicity are influenced by the spike protein and ORF 3. In general, enteric viruses (TGEV) have been shown to contain intact spike and ORF 3 genes, whilst respiratory isolates (PRCV) have major deletions within both regions. Virulence has been correlated to a functional...

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Identifiers

PMID: 10365166
DOI: 10.1007/s007050050541
PMCID: PMC7087079

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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