Article
Competition between Sec- and TAT-dependent protein translocation in Escherichia coli.
The EMBO journal - 1 Jun 1999
Cristóbal S, de Gier J W, Nielsen H, von Heijne G
Abstract excerpt
Recently, a new protein translocation pathway, the twin-arginine translocation (TAT) pathway, has been identified in both bacteria and chloroplasts. To study the possible competition between the TAT- and the well-characterized Sec translocon-dependent pathways in Escherichia coli, we have fused the TorA TAT-targeting signal peptide to the Sec-dependent inner membrane protein leader peptidase (Lep). We find that...
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