SFS, a Novel Fibronectin-Binding Protein fromStreptococcus equi, Inhibits the Binding between Fibronectin and Collagen

Abstract excerpt

The obligate parasitic bacterium Streptococcus equi subsp. equi is the causative agent of strangles, a serious disease of the upper respiratory tract in horses. In this study we have, using shotgun phage display, cloned from S. equi subsp. equi and characterized a gene, called sfs, encoding a protein termed SFS, representing a new type of fibronectin (Fn)-binding protein. The sfs gene was found to be present in...

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