Feasibility and acceptance of screening for fragile X mutations in low-risk pregnancies.

Abstract excerpt

Fragile X syndrome is the second leading cause of mental retardation after Down syndrome. Most women carriers of the fragile X mutation are unaware of their condition. We critically evaluated whether screening pregnant women at low risk for FMR1 mutation would be feasible as a routine part of antenatal care in general practice. We also studied acceptance and attitudes to gene testing. From July 1995 until...

Topics

• Feasibility Studies
• Female
• Fragile X Mental Retardation Protein
• Fragile X Syndrome
• Genetic Testing
• Health Knowledge, Attitudes, Practice
• Humans
• Intellectual Disability
• Mutation
• Nerve Tissue Proteins