Article
Mechanisms of Helicobacter pylori infection: bacterial factors.
Current topics in microbiology and immunology - 1 Jan 1999
McGee D J, Mobley H L
Abstract excerpt
Since the discovery of H. pylori in 1982 (MARSHALL 1983; WARREN 1983), research on the mechanisms of virulence of H. pylori has advanced substantially. It is now well established that urease and flagella are virulence factors of H. pylori. Although known for some time to be toxic to epithelial cells in vitro, VacA has only recently been established as a virulence factor. The cag pathogenicity island has also...
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