Article
A model for population growth of laboratory animals subjected to marker-assisted introgression: how many animals do we need?
Heredity - 1 Jan 1999
Koudandé O D, Thomson P C, van Arendonk J A
Abstract excerpt
This study provides methods for calculating the mean and variance of the number of animals with the desired genotype in each backcross generation for a marker-assisted introgression experiment. The ultimate goal is to produce animals which are homozygous for the desired loci. The methods have been developed specifically for experiments with inbred lines. The model assumes a Poisson distribution for litter size,...
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