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Budd-Chiari syndrome associated with factor V leiden mutation: a report of 6 patients.

Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society - 1 Mar 1999

Hoffman R, Nimer A, Lanir N, Brenner B, Baruch Y

Abstract excerpt

Budd-Chiari syndrome is characterized by hepatic venous outflow obstruction. Although myeloproliferative disorders are usually responsible for this severe thrombotic disorder, deficiency or dysfunction of the natural anticoagulants can be involved. Resistance to activated protein C caused by factor V Leiden mutation has been recently identified as a major cause of thrombophilia. We report 6 patients with...

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PMID: 10071347
DOI: 10.1002/lt.500050211

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Association of factor V Leiden, Janus kinase 2, prothrombin, and MTHFR mutations with primary Budd-Chiari syndrome in Egyptian patients.Semantic proximity Read ↗

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