Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Neurofibrillary Degeneration in Progressive Supranuclear Palsy and Corticobasal Degeneration

1 Mar 1999

Abstract excerpt

Pathological tau proteins that constitute the basic matrix of neuronal inclusions observed in numerous neurodegenerative disorders are disease specific. This is mainly the consequence of the aggregation of specific sets of tau isoforms according to the diseases, i.e., six isoforms in Alzheimer's disease (AD) and exclusively the three tau isoforms lacking the corresponding sequence of exon 10 (E10-) in Pick's...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Neurological diseases and metabolism
Share to Parkinson's Disease Mechanisms and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 10037497
DOI: 10.1046/j.1471-4159.1999.0721243.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Neurofibrillary Degeneration in Progressive Supranuclear Palsy and Corticobasal DegenerationPMID 10037497Read ↗

Phosphorylation of specific sets of tau isoforms reflects different neurofibrillary degeneration processesSemantic proximity Read ↗

Progressive supranuclear palsy: clinicopathological concepts and diagnostic challenges.Semantic proximity Read ↗

Clinicopathological features of the tauopathies.Semantic proximity Read ↗

Vulnerable neuronal subsets in Alzheimer's and Pick's disease are distinguished by their τ isoform distribution and phosphorylationSemantic proximity Read ↗

Invited review: Neuropathology of tauopathies: principles and practice.Semantic proximity Read ↗

Pathological inclusion bodies in tauopathies contain distinct complements of tau with three or four microtubule‐binding repeat domains as demonstrated by new specific monoclonal antibodiesSemantic proximity Read ↗

Incorporating new diagnostic schemas, genetics, and proteinopathy into the evaluation of frontotemporal degeneration.Semantic proximity Read ↗

Progress in clinical neurosciences: Frontotemporal dementia-pick's disease.Semantic proximity Read ↗

Neuropathologic, biochemical, and molecular characterization of the frontotemporal dementias.Semantic proximity Read ↗

Current concepts of neuropathological diagnostics in practice: neurodegenerative diseases.Semantic proximity Read ↗

Direct analysis of tau from PSP brain identifies new phosphorylation sites and a major fragment of N‐terminally cleaved tau containing four microtubule‐binding repeatsSemantic proximity Read ↗

Progressive supranuclear palsy: a systematic review.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.