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Article

Human factor VIII can be packaged and functionally expressed in an adeno-associated virus background: applicability to haemophilia A gene therapy.

British journal of haematology - 1 Jan 1999

Gnatenko D V, Saenko E L, Jesty J, Cao L X, Hearing P, Bahou W F

Abstract excerpt

Adeno-associated virus (AAV) is a single-stranded DNA parvovirus displaying several attractive features applicable to haemophilia A gene therapy, including nonpathogenicity and potential for long-term transgene expression from either integrated or episomal forms. We have generated and characteriz...

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Identifiers

PMID: 10027708
DOI: 10.1046/j.1365-2141.1999.01137.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-10027708-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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