Article

Synchronous Lung Adenocarcinomas With Distinct EGFR Mutations In A Patient With Li-Fraumeni Syndrome

2025-10-21

Abstract excerpt

<title>Abstract</title> <p>Li-Fraumeni syndrome (LFS) is a rare autosomal dominant hereditary disorder most frequently caused by pathogenic variants in the TP53 tumor suppressor gene, resulting in impaired regulation of cellular proliferation and apoptosis. Individuals with LFS are predisposed to a spectrum of malignancies affecting multiple organ systems, including the lungs. Lung adenocarcinoma is among the rec...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: c76af5d9-b4ab-5ac6-8318-a0a1c840300b
DOI: 10.21203/rs.3.rs-7716353/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Synchronous Lung Adenocarcinomas With Distinct EGFR Mutations In A Patient With Li-Fraumeni SyndromeDOI 10.21203/rs.3.rs-7716353/v1Read

Different EGFR gene mutations in two patients with synchronous multiple lung cancers: A case report.Semantic proximity Read

A dual biomarker in non-small cell lung cancer that predicts Li Fraumeni syndrome : Lung cancer and Li Fraumeni.Semantic proximity Read

Clinical characteristics and management of Li-Fraumeni syndrome-associated lung cancer.Semantic proximity Read

High Prevalence of Somatic Oncogenic Driver Alterations in Patients With NSCLC and Li-Fraumeni Syndrome.Semantic proximity Read

Three Primary Tumors Including EGFR-mutated Non-Small Cell Lung Cancer as First Presentation in Patient With Li-Fraumeni Syndrome.Semantic proximity Read

EGFR-mutant lung adenocarcinoma in a patient with Li-Fraumeni syndrome.Semantic proximity Read

Furmonertinib Activity in NSCLC Harboring EGFR L858R and ERBB2 S310F Co-Mutations: A Case Report With Literature ReviewSemantic proximity Read

EFGR-mutant lung adenocarcinoma and Li-Fraumeni syndrome: report of two cases and review of the literature.Semantic proximity Read

EGFR-mutated lung cancer in Li-Fraumeni syndrome.Semantic proximity Read

Different driver gene mutations in patients with synchronous multiple primary lung cancers: a case report.Semantic proximity Read

Molecular Testing in Multiple Synchronous Lung Adenocarcinomas: Case Report and Literature Review.Semantic proximity Read

Synchronous primary lung cancer and epidermal growth factor receptor mutation.Semantic proximity Read