Activation of B- and T-cells by the cytoplasmic domains of the B-cell antigen receptor proteins Ig-alpha and Ig-beta.

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Article

Activation of B- and T-cells by the cytoplasmic domains of the B-cell antigen receptor proteins Ig-alpha and Ig-beta.

The Journal of biological chemistry - 6 May 1994

Taddie J A, Hurley T R, Hardwick B S, Sefton B M

Abstract excerpt

In addition to membrane immunoglobulin (mIg), the B-cell antigen receptor contains Ig-alpha/Ig-beta heterodimers that link mIg to intracellular signaling molecules. To compare the ability of the cytoplasmic domains of Ig-alpha and Ig-beta to transduce signals in B- and T-cells, we constructed chi...

Topics

Animals
Antigens, CD
B-Lymphocytes
Base Sequence
CD79 Antigens
CD8 Antigens
Cross-Linking Reagents
DNA Primers
Humans
Immunoglobulins
Leucine
Lymphocyte Activation
Membrane Glycoproteins
Mice
Molecular Sequence Data
Mutation
Phosphorylation
Receptors, Antigen, B-Cell

Source

Open in PubMed

Identifiers

PMID: 8175787

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8175787-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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