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Article

The association between immune cells and acute kidney injury: insights from Mendelian randomization.

Renal failure - 1 Dec 2025

Yang Xianzhen, Zhang XiaoLei, Zhang Denglu, Zhao Shengtian

Abstract excerpt

BACKGROUND: Immune disorder is a prominent feature of acute kidney injury (AKI). However, the specific role of different immune cell phenotypes in the pathogenesis of AKI remains poorly understood. The aim of this study was to investigate the relevance of 731 immune phenotypes to AKI. MATERIALS AND METHODS: We obtained data on 731 immune cell phenotypes from the GWAS Catalog and Open GWAS databases and undertook...

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Acute Kidney Injury
B-Lymphocytes
CD24 Antigen
Dendritic Cells
Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Interleukin-2 Receptor alpha Subunit

Mendelian Randomization Analysis

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Identifiers

PMID: 41844385
DOI: 10.1080/0886022X.2025.2471011
PMCID: PMC11878167

Genes

CD24

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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