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Article

Identification of Shared Genetic Loci Associated With Inflammatory Bowel Disease, Ischemic Heart Disease, and Atrial Fibrillation and Flutter.

Clinical genetics - 1 Sept 2025

Chen Guojian, Luo Qinghua, Wu Chengcheng, Xie Mingjun

Abstract excerpt

The occurrence of ischemic heart disease (IHD), atrial fibrillation, and flutter demonstrates certain associations with inflammatory bowel disease (IBD), warranting further exploration at the genetic architecture level. This study focused on genome-wide association study (GWAS) data of IHD, atrial fibrillation and flutter, and IBD, analyzing from two dimensions: genetic correlation and shared locus...

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Share to Atrial Fibrillation
Share to Genetic Loci
Share to Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Inflammatory Bowel Diseases

Share to Linkage Disequilibrium

Share to Mendelian Randomization Analysis

Share to Myocardial Ischemia

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 40343385
DOI: 10.1111/cge.14749

Genes

ERAP2
GNA12
MTHFS
PLCG2
PTPN22
RP1
SMAD3
ZMIZ1
ZNF831

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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