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Cardiovascular health, polygenic risk score, and cancer risk: a prospective cohort study.

The American journal of clinical nutrition - 1 Oct 2024

Peng Yu, Wang Peng, Du Han, Liu Fubin, Wang Xixuan, Si Changyu, Gong Jianxiao, Zhou Huijun, Chen Kexin, Song Fangfang

Abstract excerpt

BACKGROUND: Cancer and cardiovascular disease share common lifestyle risk factors. However, it remains unclear whether cardiovascular health (CVH) evaluated by Life's Essential 8 can predict cancer risk, and attenuate the influence of genetic susceptibility on cancer. OBJECTIVES: We aimed to evaluate independent and joint associations of CVH and polygenic risk score (PRS) with risks of overall and site-specific...

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Identifiers

PMID: 39134210
DOI: 10.1016/j.ajcnut.2024.07.033

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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