Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epigenetic Age Mediates the Association of Life's Essential 8 With Cardiovascular Disease and Mortality

29 May 2024

Abstract excerpt

Background Life's Essential 8 (LE8) is an enhanced metric for cardiovascular health. The interrelations among LE8, biomarkers of aging, and disease risks are unclear. Methods and Results LE8 score was calculated for 5682 Framingham Heart Study participants. We implemented 4 DNA methylation‐based epigenetic age biomarkers, with older epigenetic age hypothesized to represent faster biological aging, and examined...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiovascular Health and Risk Factors
Share to Epigenetics and DNA Methylation
Share to Health, Environment, Cognitive Aging

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38808571
DOI: 10.1161/jaha.123.032743

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epigenetic Age Mediates the Association of Life's Essential 8 With Cardiovascular Disease and MortalityPMID 38808571Read ↗

Life's Essential 8, Genetic Susceptibility, and Incident Cardiovascular Disease: A Prospective Study.Semantic proximity Read ↗

Comparative validation of an epigenetic mortality risk score with three aging biomarkers for predicting mortality risks among older adult malesSemantic proximity Read ↗

Relation of Life's Essential 8 to the genetic predisposition for cardiovascular outcomes and all-cause mortality: results from a national prospective cohort.Semantic proximity Read ↗

Life's Essential 8, genetic susceptibility, and risk of cognitive impairment: results from an elder population-based cohort study.Semantic proximity Read ↗

Oxidative Stress Factors Mediate the Association Between Life’s Essential 8 and Accelerated Phenotypic Aging: NHANES 2005–2018Semantic proximity Read ↗

Impact of genetic risk and lifestyles on cardiovascular disease-free and total life expectancy: a cohort study.Semantic proximity Read ↗

Life's Essential 8, Genetic Susceptibility, and the Risk of Age-Related Macular Degeneration: A Prospective Cohort Study.Semantic proximity Read ↗

Heritability of and mortality prediction with a longevity phenotype: the healthy aging index.Semantic proximity Read ↗

Intergenerational and life-course links between a cardiovascular health-related methylation score and early vascular changesSemantic proximity Read ↗

DNA Methylation Signatures of Cardiovascular Health Provide Insights Into DiseasesSemantic proximity Read ↗

Association of cardiovascular health and epigenetic age accelerationSemantic proximity Read ↗

Association of Life's Essential 8 cardiovascular health with breast cancer incidence and mortality according to genetic susceptibility of breast cancer: a prospective cohort study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.