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Signatures of malignant cells and novel therapeutic targets revealed by single‐cell sequencing in lung adenocarcinoma

31 Jan 2022

Abstract excerpt

BACKGROUND: Single-cell transcriptomics has been used to investigate various tumors to elucidate the molecular distinction of all cell type compositions of a complex mix. AIMS: This study aimed to investigate malignant-cell-specific genes to explore diagnostic and therapeutic biomarkers using single-cell transcriptomic data of lung adenocarcinoma. MATERIALS & METHODS: 10X single-cell RNA-seq data of fourteen...

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Cancer Immunotherapy and Biomarkers
Ferroptosis and cancer prognosis
Single-cell and spatial transcriptomics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35102706
DOI: 10.1002/cam4.4547

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