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RAD51 is a potential marker for prognosis and regulates cell proliferation in pancreatic cancer

1 Dec 2019

Abstract excerpt

BACKGROUND: The DNA damage and repair pathway is considered a promising target for developing strategies against cancer. RAD51, also known as RECA, is a recombinase that performs the critical step in homologous recombination. RAD51 has recently received considerable attention due to its function in tumor progression and its decisive role in tumor resistance to chemotherapy. However, its role in pancreatic cancer...

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PMID: 31889908
DOI: 10.1186/s12935-019-1077-6

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