Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dynamic autophagic activity affected the development of thoracic aortic dissection by regulating functional properties of smooth muscle cells.

Biochemical and biophysical research communications - 14 Oct 2016

Wang Yang, Zhao Zhi-Min, Zhang Guan-Xin, Yang Fan, Yan Yan, Liu Su-Xuan, Li Song-Hua, Wang Guo-Kun, Xu Zhi-Yun

Abstract excerpt

The aortic medial degeneration is the key histopathologic feature of Thoracic aortic dissection (TAD). The aim of this study was to identify the change of autophagic activity in the aortic wall during TAD development, and to explore the roles of autophagy on regulating functional properties of smooth muscle cells (SMCs). Firstly, compared with control group (n = 11), the increased expression of autophagic markers...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiotensin II
Share to Aorta, Thoracic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aortic Dissection

Share to Autophagy

Share to Beclin-1

Share to Elasticity

Share to Microscopy, Electron, Transmission

Share to Myocytes, Smooth Muscle

Source

Identifiers

PMID: 27644881
DOI: 10.1016/j.bbrc.2016.09.080

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dynamic autophagic activity affected the development of thoracic aortic dissection by regulating functional properties of smooth muscle cells.PMID 27644881Read ↗

Exaggerated Autophagy in Stanford Type A Aortic Dissection: A Transcriptome Pilot Analysis of Human Ascending Aortic TissuesSemantic proximity Read ↗

C/EBPα-Mediated Transcriptional Activation of PIK3C2A Regulates Autophagy, Matrix Metalloproteinase Expression, and Phenotypic of Vascular Smooth Muscle Cells in Aortic Dissection.Semantic proximity Read ↗

Identification of the key ferroptosis-related genes in the pathogenesis of thoracic aortic dissection and thoracic aortic aneurysm using integrated bioinformatic analysis and experimental verificationSemantic proximity Read ↗

Supplementary Elevated triglycerides predispose patients to aortic dissection by increasing inflammasome-induced pyroptosisSemantic proximity Read ↗

Tirzepatide mitigates thoracic aortic aneurysm and dissection by alleviating the loss of the contractile phenotype in vascular smooth muscle cells and reducing vascular inflammation.Semantic proximity Read ↗

The role of autophagy in cardiovascular disease: Cross-interference of signaling pathways and underlying therapeutic targetsSemantic proximity Read ↗

Role of Necroptosis and Immune Infiltration in Human Stanford Type A Aortic Dissection: Novel Insights from Bioinformatics AnalysesSemantic proximity Read ↗

Lack of evidence for the involvement of non-canonical pyroptosis in a mouse model of thoracic aortic dissection.Semantic proximity Read ↗

Role of Endoplasmic Reticulum Stress, Autophagy, and Inflammation in Cardiovascular DiseaseSemantic proximity Read ↗

Transcriptome Insights into Protective Mechanisms of Ferroptosis Inhibition in Aortic DissectionSemantic proximity Read ↗

ACE2 deficiency inhibits thoracic aortic dissection by enhancing SIRT3 mediated inhibition of inflammation and VSCMs phenotypic switch.Semantic proximity Read ↗

Proliferative, degradative smooth muscle cells promote aortic disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.