Article
The carbapenem inactivation method (CIM), a simple and low-cost alternative for the Carba NP test to assess phenotypic carbapenemase activity in gram-negative rods.
PloS one - 1 Jan 2015
van der Zwaluw Kim, de Haan Angela, Pluister Gerlinde N, Bootsma Hester J, de Neeling Albert J, Schouls Leo M
Abstract excerpt
A new phenotypic test, called the Carbapenem Inactivation Method (CIM), was developed to detect carbapenemase activity in Gram-negative rods within eight hours. This method showed high concordance with results obtained by PCR to detect genes coding for the carbapenemases KPC, NDM, OXA-48, VIM, IMP and OXA-23. It allows reliable detection of carbapenemase activity encoded by various genes in species of...
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