Article
The pharmacogenetics of codeine pain relief in the postpartum period.
The pharmacogenomics journal - 1 Oct 2015
Baber M, Chaudhry S, Kelly L, Ross C, Carleton B, Berger H, Koren G
Abstract excerpt
The objective of this study was to examine interindividual variability in codeine requirements and pain management by examining select genetic polymorphisms in the codeine pharmacological pathway. The study included a nested cohort of 98 women who were prescribed codeine following cesarean section. Participants were genotyped for select polymorphisms of the COMT, ABCB1, CYP2D6, UGT2B7 and OPRM1 genes and...
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