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Article

Characterization of neuraminidases from the highly pathogenic avian H5N1 and 2009 pandemic H1N1 influenza A viruses.

PloS one - 29 Dec 2010

Wu Jia, Zhang Fengwei, Wang Maorong, Xu Chunqiong, Song Jingdong, Zhou Jianfang, Lin Xiaojing, Zhang Yonghui, Wu Xiaobing, Tan Wenjie, Lu Jian, Zhao Honglan, Gao Jimin, Zhao Ping, Lu Jianxin, Wang Yue

Abstract excerpt

To study the precise role of the neuraminidase (NA), and its stalk region in particular, in the assembly, release, and entry of influenza virus, we deleted the 20-aa stalk segment from 2009 pandemic H1N1 NA (09N1) and inserted this segment, now designated 09s60, into the stalk region of a highly pathogenic avian influenza (HPAI) virus H5N1 NA (AH N1). The biological characterization of these wild-type and mutant...

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Identifiers

PMID: 21209916
DOI: 10.1371/journal.pone.0015825
PMCID: PMC3012118

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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