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Article

Principal-component analysis for assessment of population stratification in mitochondrial medical genetics.

American journal of human genetics - 11 Jun 2010

Biffi Alessandro, Anderson Christopher D, Nalls Michael A, Rahman Rosanna, Sonni Akshata, Cortellini Lynelle, Rost Natalia S, Matarin Mar, Hernandez Dena G, Plourde Anna, de Bakker Paul I W, Ross Owen A, Greenberg Steven M, Furie Karen L, Meschia James F, Singleton Andrew B, Saxena Richa, Rosand Jonathan

Abstract excerpt

Although inherited mitochondrial genetic variation can cause human disease, no validated methods exist for control of confounding due to mitochondrial population stratification (PS). We sought to identify a reliable method for PS assessment in mitochondrial medical genetics. We analyzed mitochond...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20537299
DOI: 10.1016/j.ajhg.2010.05.005
PMCID: PMC3032075

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20537299-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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