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Article

Stepwise regression analysis of the determinants of blood tacrolimus concentrations in Chinese patients with liver transplant.

Medicinal chemistry (Shariqah (United Arab Emirates)) - 1 May 2009

Jin Z, Zhang W X, Chen B, Mao A W, Cai W M

Abstract excerpt

Tacrolimus (FK506) is one of the immunosuppressive drugs used effectively to prevent allograft rejection after liver transplantation. Narrow therapeutic range and individual variance in pharmacokinetics make it difficult to establish a fixed dosage for all patients. Genetic polymorphism in drug metabolizing enzymes and in transporters may influence tacrolimus exposure. A stepwise regression analysis was used to...

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PMID: 19442221
DOI: 10.2174/157340609788185918

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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