Article
Safety of codeine during breastfeeding: fatal morphine poisoning in the breastfed neonate of a mother prescribed codeine.
Canadian family physician Medecin de famille canadien - 1 Jan 2007
Madadi Parvaz, Koren Gideon, Cairns James, Chitayat David, Gaedigk Andrea, Leeder J Steven, Teitelbaum Ronni, Karaskov Tatyana, Aleksa Katarina
Abstract excerpt
QUESTION: Recently a newborn died from morphine poisoning when his mother used codeine while breastfeeding. Many patients receive codeine for postlabour pain. Is it safe to prescribe codeine for nursing mothers? ANSWER: When a mother is an ultrarapid metabolizer of cytochrome P450 2D6, she produces much more morphine when taking codeine than most people do. In this situation, newborns might be exposed to toxic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.