Article
Binding of aryl hydrocarbon receptor (AhR) to AhR-interacting protein. The role of hsp90.
The Journal of biological chemistry - 17 Nov 2000
Bell D R, Poland A
Abstract excerpt
The aryl hydrocarbon receptor (AhR) has been shown to interact with an immunophilin-like molecule known as AhR-interacting protein (AIP) and to enhance AhR function. We show here that AIP associates with AhR homologues from mouse and fish, which can bind ligands such as dioxin, but nonligand binding homologues from Caenorhabditis elegans or Drosophila do not bind to AIP. However, a minimal ligand-binding domain...
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