Noncoding Variant to Target Gene Mapping

Cell state in target-gene evidence synthesis

by Ansel W.

When synthesizing noncoding variant studies, what information distinguishes conflicting target-gene assignments from assignments that apply to different cell states?

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mistyshadow99

Record which donor populations contribute evidence for each cell state. Suppose two target-gene assignments come from different cell states sampled in entirely different donor populations. That comparison alone cannot separate cell-state differences from donor-population differences.

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